Motherwell will start their Betfred Cup campaign with a home match against Edinburgh City on Tuesday, 17 July.
The Steelmen, beaten finalists in the 2017/18 competition, will sit out the first day of group stage action on 14 July.
A trip to Stranraer will follow on Saturday, 21 July, before Queen of the South are visitors to Fir Park on Tuesday, 24 July.
The final match of the group stage away to Clyde on Saturday, 28 July will be broadcast live on BT Sport.
As was the case in the previous two seasons, group stage matches will be played in the traditional format of three points for the winner after 90 minutes.
In the event of a draw, both teams will be awarded a point but a bonus point will be on offer for the winner of a penalty shootout at the end of 90 minutes of play.
The group winners and four best runners up will then progress to the last 16, where they will be joined by Aberdeen, Celtic, Hibernian and Rangers.
This season’s final will be played on Sunday, 2 December.
BETFRED CUP FIXTURES
Tuesday, 17 July: Edinburgh City (H), 7.45pm
Saturday, 21 July: Stranraer (A), 3pm
Tuesday, 24 July: Queen of the South (H), 7.45pm
Saturday, 28 July: Clyde (A), 3pm, live on BT Sport